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Updated Jun 16, 2018 7 subscribers

Anomaly Detection

Editor Jordan Anaya

Seeking and reporting apparent research misconduct: errors and integrity (2018)

E. D. Kharasch, T. T. Houle

DOI: 10.1111/anae.14147  PubMed: 29210039 

This publication takes issue with Carlisle's analysis of 5,087 trials, and the accompanying editorial.

A reply by the authors of the editorial was posted: https://onlinelibrary.wiley.com/doi/full/10.1111/anae.14170

Essentially, we have a scientific dispute and I'm here to resolve it.

I have to side with Carlisle and the authors of the editorial. The paper claims that there are a bunch of reasons why a trial might be flagged by Carlisle's method besides fraud...which was already echoed by Carlisle himself.

The paper also claims Carlisle's method is relying on "an illogic foundation", but that doesn't stop them from using the method in a simulation anyways. The dirty secret is a simulation can be used to show whatever you want it to show. To guard against this, you should try to have your simulation be as faithful as possible to reality. The authors should have bootstrapped the properties of Carlisle's data, but did not. As a result, I cannot take anything of value from their simulation.

They also take offense that the data was not deidentified. I don't think any of these papers are going to get retracted simply because they showed up at the top of Carlisle's list, so it's hard to imagine any of these researchers will suffer any long term consequences unless an investigation finds there are problems with the articles.

The bias of these authors seeps through the pages, who are simply trying to defend the articles flagged in their journal. Given the unnecessary fearmongering of this article and the fact it adds nothing to the conversation, I am rejecting this article.

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