Accelerated Development of a Scalable Ring-Closing Metathesis to Manufacture AMG 176 Using a Combined High-Throughput Experimentation and Computational Modeling Approach (2020)

Gabrielle St-Pierre, Alan H. Cherney, Wencan Chen, Xiaofei Dong, Peter K. Dornan, Daniel J. Griffin, K. N. Houk, Janice B. Lin, Stephen Osgood, Maria V. Silva Elipe, Heath C. Timmons, Yong Xie, Jason S. Tedrow, Oliver R. Thiel, Austin G. Smith

DOI: 10.1021/acs.oprd.0c00416