Collecting papers on computational modelling, understanding and inference of transcriptional regulatory interactions in cells
Editor Martin Modrák
Fundamental limits on dynamic inference from single-cell snapshots (2018)
Caleb Weinreb, Samuel Wolock, Betsabeh K. Tusi, Merav Socolovsky, Allon M. Klein
PubMed: 29463712 DOI: 10.1073/pnas.1714723115
A must-read for anyone trying to do inference from single-cell data, the paper shows that rules governing cell evolution cannot generally be inferred from single-cell data. The authors also show how adding additional assumptions can lead to a tractable problem.