The Science Reach
The journal of group 3 in the course Effective Science Communication at DTU
Editor
Katrin Birna, Johannesdottir
Coronavirus biology and replication: implications for SARS-CoV-2 (2021)
Philip V’kovski, Annika Kratzel, Silvio Steiner, Hanspeter Stalder, Volker Thiel
DOI: 10.1038/s41579-020-00468-6 PubMed: 33116300
The authors are describing the potential of Virusend (TX-10) as a detergent for inactivation of SARS-CoV-2. They concluded that the use of the above mentioned detergent can reduce the viral concentration, by both solution and surface inactivation, by a 4log PFU/ml within a minute ensuring that the use of disinfectants is crucial for the elimination of the spread of SARS-CoV-2 and the control of the COVID-19 pandemic.
The manuscript is in general well written with a good flow and language. Easy to read and without any unnecessary information. However, the authors miss to provide information about the common concentrations of the virus on a contaminated area. In this case we do not know if a 4log reduction is enough to completely eliminate the virus. Therefore, the manuscript is accepted with some minor revisions:
-Provide information of previous research if available on what are the concentrations that the virus is usually found on surfaces that have been naturally contaminated.
-L104-107: Could that LOD be determined to a lower concentration?
-Fig 2. In the text above (L121 and L122) you are referring to fig 2A and 2B which are missing on your figure.
-L178-179: if the effectiveness of other types of detergents against SARS-CoV-2 has been already proved then why did the authors chose to study the particular detergent?
Editors note: Accepted with minor revision
Subjects
A peeriodical is a lightweight virtual journal with you as the Editor-in-chief, giving you complete freedom in setting editorial policy to select the most interesting and useful manuscripts for your readers. The manuscripts you will evaluate and select are existing publications—preprints and papers. Thus, a peeriodical replicates all the functions of a traditional journal, including discovery, selection and certification, except publication itself.
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