Theory of spike initiation, sensory systems, autonomous behavior, epistemology
Editor Romain Brette
Cleaning patch-clamp pipettes for immediate reuse (2016)
I. Kolb, W. A. Stoy, E. B. Rousseau, O. A. Moody, A. Jenkins, C. R. Forest
PubMed: 27725751 DOI: 10.1038/srep35001
This is a simple but very interesting study where the authors show that it is possible to clean patch clamp pipettes in Alconox up to 10 times, and reuse the pipettes on different cells with no noticeable effect. This is what was missing to truly automate patch clamp, as it was previously necessary to manually change the pipette after every recorded cell (or failed attempt).