Theory of spike initiation, sensory systems, autonomous behavior, epistemology
Editor Romain Brette
The nano-architecture of the axonal cytoskeleton (2017)
Christophe Leterrier, Pankaj Dubey, Subhojit Roy
PubMed: 29097785 DOI: 10.1038/nrn.2017.129
This is a very interesting review on recent discoveries about the axonal cytoskeleton, which have been made possible in particular by super-resolution microscopy. One of these discoveries is the actin rings that are periodically spaced along the axon. The roles of these rings are not entirely clear, but probably mechanical robustness is one of them. As channels attach to the cytoskeleton, one also wonders whether these periodic rings might also be involved in the regulation of channel density.