Papers selected and presented by PhD student Jonathan Temple (he will officially become Editor once he has published his first article).
Editor Raphaël Lévy
Paper supported long-term 3D liver co-culture model for the assessment of hepatotoxic drugs (2018)
Yaqing Wang, Wentao Su, Li Wang, Lei Jiang, Yang Liu, Lijian Hui, Jianhua Qin
http://www.ncbi.nlm.nih.gov/pubmed/30090558
Nov 20, 2018 - Paper is an attractive biocompatible material for cell-based applications due to its biocompatibility. In this study, Wang et al. established a simple paper-based scaffold array for creating a 3D liver co-culture model that enabled the assessment of drug induced hepatotoxicity. Usi...
Jessica H. Brown, Prativa Das, Michael D. DiVito, David Ivancic, Lay Poh Tan, Jason A. Wertheim
http://www.ncbi.nlm.nih.gov/pubmed/29454157
Nov 20, 2018 - Brown et al. developed a three-dimensional (3D) nanofibrous scaffold made from poly(L-lactide-co-glycolide) (PLGA) polymer using a newly optimized wet electrospinning technique. The resulting scaffold had a highly porous structure when compared with conventional ‘dry’ electro-spun ...
Development of a 3D cell printed construct considering angiogenesis for liver tissue engineering (2016)
Jin Woo Lee, Yeong-Jin Choi, Woon-Jae Yong, Falguni Pati, Jin-Hyung Shim, Kyung Shin Kang, In-Hye Kang, Jaesung Park, Dong-Woo Cho
http://www.ncbi.nlm.nih.gov/pubmed/26756962
Sep 26, 2018 - This article demonstrates a novel 3D cell printing technology and its application in liver tissue engineering. Currently the poor mechanical properties of cell-laden hydrogels cause issues during the printing process. Using polycaprolactone (PCL) as a framework material Lee et al ...
Multi-cellular 3D human primary liver cell culture elevates metabolic activity under fluidic flow (2015)
Mandy B. Esch, Jean-Matthieu Prot, Ying I. Wang, Paula Miller, Jose Ricardo Llamas-Vidales, Brian A. Naughton, Dawn R. Applegate, Michael L. Shuler
http://www.ncbi.nlm.nih.gov/pubmed/25857666
Sep 07, 2018 - This article uses a macroporous polymer scaffold to culture multiple liver cell types simultaneously under flow conditions. It compares scaffolds cultured under flow or static conditions and finds that flow results in elevations of both albumin and urea excretion; however, flow app...