Peeriodicals

3DbioNet - discussing 3D cell biology

This Peeriodical is a platform for scientists with interest in 3D biology field to review and discuss recent or older publications. 3DbioNet is a UK network (@3DbioNet) and we are facilitating this journal club because we believe that robust discussion of science is essential, especially in an interdisciplinary field like ours. Individual reviews are signed - they represent the expert views of their authors, not those of all Editors, 3DbioNet or its management board. We hope this space for scientific discussion will benefit all the 3DbioNet network members in their current and future research, to improve the robustness of research outputs, identify problems, and share new ideas/protocols to improve our working practices.

3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments (2019)

Fanben Meng, Carolyn M. Meyer, Daeha Joung, Daniel A. Vallera, Michael C. McAlpine, Angela Panoskaltsis-Mortari

http://www.ncbi.nlm.nih.gov/pubmed/30663123

Jun 11, 2020 - Review by Dr. Priyanka Gupta, University of Surrey, UK. This publication by Meng et al., 2019 attempts to create an in vitro metastasis model of tumour microenvironment (TME) using lung cancer as a model system. The paper employs multiple techniques including 3D bioprinting, stimul...

Accordion-like honeycombs for tissue engineering of cardiac anisotropy (2008)

George C. Engelmayr, Mingyu Cheng, Christopher J. Bettinger, Jeffrey T. Borenstein, Robert Langer, Lisa E. Freed

http://www.ncbi.nlm.nih.gov/pubmed/18978786

Jun 01, 2020 - Presented on 24.04.20 for the 3DbioNet online journal club Annabelle Fricker from the Department of Materials Science and Engineering, Faculty of Engineering, University of Sheffield, supervised by Professor Ipsita Roy. This paper reports the production of 3D scaffolds for cardiac ...

Aggregated P19 mouse embryonal carcinoma cells as a simple in vitro model to study the molecular regulations of mesoderm formation and axial elongation morphogenesis (2009)

Yusuke Marikawa, Dana Ann A. Tamashiro, Toko C. Fujita, Vernadeth B. Alarcón

http://www.ncbi.nlm.nih.gov/pubmed/19115346

May 29, 2019 - In this paper (1), Marikawa et al. use P19 embryonal carcinoma (EC) cells grown as 3D aggregates to study the properties of early axial development, specifically mesendodermal formation and axial elongation. Although this paper is now 10 years old, it is in my opinion, an important...

Familial Alzheimer’s disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta (2020)

Charles Arber, Jamie Toombs, Christopher Lovejoy, Natalie S. Ryan, Ross W. Paterson, Nanet Willumsen, Eleni Gkanatsiou, Erik Portelius, Kaj Blennow, Amanda Heslegrave, Jonathan M. Schott, John Hardy, Tammaryn Lashley, Nick C. Fox, Henrik Zetterberg, Selina Wray

http://dx.doi.org/10.1038/s41380-019-0410-8

May 24, 2019 - This paper (Arber et al. 2019) describes the occurrence of different Amyloid beta peptides generated by human cells with different Amyloid Precursor Protein (APP) or Presenilin 1 mutations, related to Alzheimer’s disease. Although the primary aim of the paper is not to compare 2D v...

Blended electrospinning with human liver extracellular matrix for engineering new hepatic microenvironments (2019)

Rhiannon Grant, John Hallett, Stuart Forbes, David Hay, Anthony Callanan

http://www.ncbi.nlm.nih.gov/pubmed/31000735

May 14, 2019 - The authors report the preparation and application of electrospun scaffolds incorporating either a single protein (Laminin, collagen or fibronectin) or an extracellular matrix preparation from donated human livers (hlECM) in a poly-L-lactic acid matrix. The hlECM preparation is obt...

3DbioNet - discussing 3D cell biology

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