A selection of papers relating to the computational side of infectious disease biology.
Editors Matt Ravenhall Benjamin Sobkowiak Ernest Diez Benavente Yaa Oppong
Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis (2018)
Francesc Coll, Jody Phelan, Grant A. Hill-Cawthorne, Mridul B. Nair, Kim Mallard, Shahjahan Ali, Abdallah M. Abdallah, Saad Alghamdi, Mona Alsomali, Abdallah O. Ahmed, Stephanie Portelli, Yaa Oppong, Adriana Alves, Theolis Barbosa Bessa, Susana Campino, Maxine Caws, Anirvan Chatterjee, Amelia C. Crampin, Keertan Dheda, Nicholas Furnham, Judith R. Glynn, Louis Grandjean, Dang Minh Ha, Rumina Hasan, Zahra Hasan, Martin L. Hibberd, Moses Joloba, Edward C. Jones-López, Tomoshige Matsumoto, Anabela Miranda, David J. Moore, Nora Mocillo, Stefan Panaiotov, Julian Parkhill, Carlos Penha, João Perdigão, Isabel Portugal, Zineb Rchiad, Jaime Robledo, Patricia Sheen, Nashwa Talaat Shesha, Frik A. Sirgel, Christophe Sola, Erivelton Oliveira Sousa, Elizabeth M. Streicher, Paul Van Helden, Miguel Viveiros, Robert M. Warren, Ruth McNerney, Arnab Pain, Taane G. Clark
http://www.ncbi.nlm.nih.gov/pubmed/29358649
Jun 21, 2018 - The evolution of drug resistance in Mycobacterium tubercolosis, the causal pathogen for tuberculosis, poses a thread to global disease control efforts. Using a large global dataset (6,465 Mycobacterium tubercolosis isolates) and genome-wide methodologies, this paper identifies nove...
Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strain (2015)
Vegard Eldholm, Johana Monteserin, Adrien Rieux, Beatriz Lopez, Benjamin Sobkowiak, Viviana Ritacco, Francois Balloux
http://www.ncbi.nlm.nih.gov/pubmed/25960343
Jun 06, 2018 - The rise of drug-resistant strains is a major challenge to containing the tuberculosis (TB) pandemic. Yet, little is known about the extent of resistance in early years of chemotherapy and when transmission of resistant strains on a larger scale became a major public health issue. ...
Rebecca Johnson, Matt Ravenhall, Derek Pickard, Gordon Dougan, Alexander Byrne, Gad Frankel
http://www.ncbi.nlm.nih.gov/pubmed/29229736
Jun 06, 2018 - Salmonella Typhi is the causal pathogen for Typhoid fever, a significant global disease which caused 12.5 million cases and 149,000 deaths in 2015 alone. Yet, to date, most research is conducted with the related, but distinct, mouse model Salmonella Typhimurium. This paper utilises...
Matt Ravenhall, Ernest Diez Benavente, Mwapatsa Mipando, Anja T. R. Jensen, Colin J. Sutherland, Cally Roper, Nuno Sepúlveda, Dominic P. Kwiatkowski, Jacqui Montgomery, Kamija S. Phiri, Anja Terlouw, Alister Craig, Susana Campino, Harold Ocholla, Taane G. Clark
http://www.ncbi.nlm.nih.gov/pubmed/27899115
Jun 06, 2018 - SP resistance in malaria is an often overlooked subset of anti-malarial resistance literature, with focus tending to be upon chloroquine or ACT resistance. This is despite SP still being used for Intermittent preventive treatment in pregnancy (IPTp) and Seasonal Malaria Chemopreven...