Personalized medicine: modeling, diagnosis, & treatment
Providing a forum for research that uses patient-specific data or models to select or design the right treatment for individual patients.
Editor Daniel J Cook
Genome-scale metabolic models applied to human health and disease (2017)
Daniel J Cook, Jens Nielsen
http://www.ncbi.nlm.nih.gov/pubmed/28644920
Jul 13, 2018 - This review describes the challenges facing researchers in the use of GEMs, the approaches used to address these challenges, and advances that are on the horizon and could lead to a better understanding of human metabolism.
Personalized Prediction of Proliferation Rates and Metabolic Liabilities in Cancer Biopsies (2016)
Christian Diener, Osbaldo Resendis-Antonio
http://www.ncbi.nlm.nih.gov/pubmed/28082911
Jul 13, 2018 - This study uses transcriptomic data to predict growth rates in single tumors, then uses metabolic modeling constrained based on the predicted growth rates to predict metabolic liabilities in individual patient cancers.
