Good overview of the myriad of function of a classical cytokine that binds all immunologist-alike together: IFNγ

Take home message quote adapted from text ''Advancement of our knowledge of IFNγ functions and mechanisms of action can be harnessed to develop new therapeutic strategies to improve host defence, suppress autoimmunity and augment responses to various cancer therapies, including in patients with tumours resistant to currently available therapeutics.''

Highlights -Overview -Programming of macrophages by IFNγ -Epigenetic regulation by IFNγ -Regulation of macrophage metabolism by IFNγ -Regulation of other immune cells by IFNγ -IFNγ in tissue-specific pathology -Pivotal role of IFNγ in cancer immunotherapy