Cool papers about methods for and applications of label-free optical microscopy (i.e., imaging using the structures and molecules already present in cells and tissues).
Editors Daniel A. Gil Wilson R. Adams
Select publications relating to label-free optical microscopy and imaging, which includes techniques such as: Non-linear Optical Microscopy (NLOM), Autofluorescence Multiphoton Microscopy and Fluorescence Lifetime Imaging Microscopy (Autofluorescence MPM, FLIM), Coherent Raman Microscopy: Stimulated Raman Scattering (SRS) & Coherent Anti-Stokes Raman Scattering (CARS), Sum Frequency Generation Microscopy (SFG), Second/Third Harmonic Microscopy (SHG, THG), Optical Coherence Tomography/Microscopy (OCT/OCM), Quantitative Phase Imaging (QPI) & Holography, Polarization Microscopy/Imaging, Photoacoustic Imaging/Tomography/Microscopy (PAI/PAT/PAM)
Label-Free Vibrational Spectroscopic Imaging of Neuronal Membrane Potential (2017)
Hyeon Jeong Lee, Delong Zhang, Ying Jiang, Xiangbing Wu, Pei-Yu Shih, Chien-Sheng Liao, Brittani Bungart, Xiao-Ming Xu, Ryan Drenan, Edward Bartlett, Ji-Xin Cheng
http://www.ncbi.nlm.nih.gov/pubmed/28407470
Jul 15, 2018 - Neurons in our brains communicate through action potentials, and researchers use these to assess and interpret neural activity. The current, widely-accepted methods of measuring action potentials are either direct, like electrophysiology and voltage-sensitive dyes/proteins, or indi...
Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy (2018)
Sixian You, Haohua Tu, Eric J. Chaney, Yi Sun, Youbo Zhao, Andrew J. Bower, Yuan-Zhi Liu, Marina Marjanovic, Saurabh Sinha, Yang Pu, Stephen A. Boppart
http://www.ncbi.nlm.nih.gov/pubmed/29844371
Jun 19, 2018 - Many label-free microscopy techniques exploit nonlinear optical effects for contrast. These require ultrashort pulses generated from sources like Ti:Sapphire lasers directly or Ti:Saph-pumped OPOs. Multiplexed imaging is then generally performed via sequential acquisition to allow ...