Morgridge Institute for Research & University of Wisconsin–Madison
I am a graduate researcher working with Melissa Skala, Medical Engineering, to develop label-free optical imaging technologies and quantitative image analysis methods. I was immediately captivated by the concept of label-free optical imaging: By using light in just the right way, you can image intact, biological tissue using the structures and molecules already present. This means we can use the same technique to study disease in patients as easily as in model organisms. My current research focuses on two label-free technologies, optical coherence tomography and autofluorescence microscopy. Each technology poses specific challenges to existing image analysis tools, so I mostly work on new analysis methods that can extract robust, quantitative information from these images, even in the presence of noise and artifacts. My goal is to enable these label-free technologies to solve problems in areas like tissue engineering, neurosurgery, respiratory medicine, and precision oncology.
Cool papers about methods for and applications of label-free optical microscopy (i.e., imaging using the structures and molecules already present in cells and tissues).
A peeriodical is a lightweight virtual journal with you as the Editor-in-chief, giving you complete freedom in setting editorial policy to select the most interesting and useful manuscripts for your readers. The manuscripts you will evaluate and select are existing publications—preprints and papers. Thus, a peeriodical replicates all the functions of a traditional journal, including discovery, selection and certification, except publication itself.
Why set up a peeriodical? The traditional journal has changed remarkably little in centuries and many people feel that scientific publishing is stuck in a rut, subject to a corporatist drift, and is not serving science optimally. The advent of preprints in many fields beyond those served by the ArXiv is liberating the dissemination of research, but most other journal functions have not been replaced effectively. Now you—all researchers—have the opportunity to select and certify research according to your own criteria. We expect peeriodical subject matters and editorial policies to be extremely varied. Some peeriodicals may wish to target narrow domains, while others will adopt a generalist approach. Some peeriodicals will be inclusive, focusing on discovery, whereas others may aim to enforce stringent quality criteria, prioritising certification. The point is that all approaches are permitted and supported—we hope you will innovate! You can create multiple peeriodicals. It will be users and readers who decide which peeriodicals they find useful and interesting. Users can sign up to receive alerts from any peeriodical they wish.
A peeriodical has one or more editors. Anybody can set-up a peeriodical and either operate it alone or invite colleagues to form an editorial board or community. The editors can select "manuscripts"—existing papers or preprints—to consider, either spontaneously or through suggestions from other researchers, including of course the authors. Note that there is no obligation that the manuscript be recent; for instance, we expect that some peeriodicals could focus on underappreciated classics. After all, predictions about scientific impact are generally more accurate for the past than the future. If the editors wish, they can solicit reviews for the manuscript via the Peeriodicals interface. Reviews will be published and the referees will have the option of posting anonymously or signing their review. Editors may decide at any time to accept, reject or comment on the manuscript, taking into account the comments received. They may of course suggest improvements to the manuscript or underlying study. If they justify their decision, their editorial decision will also be published.
How will Peeriodicals fit into the publishing landscape? We see them as a space without entry barriers in which researchers can innovate and explore new approaches to scientific dissemination, in parallel to the traditional publishing industry. There are related and complementary initiatives, notably the overlay journals promoted by Tim Gowers, exemplified by Discrete Analysis, but also Science Open Collections, PLoS Channels, the APPRAISE initiative and Peer Community in... Each of these projects has their own specificities and goals. Nobody yet knows exactly what the future will look like, but we strongly believe that we are about to experience a period of rapid evolution in the dissemination of science and we hope that Peeriodicals will inspire and help you to share your imagination and expertise with the whole research community.
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